Red and Liz catch wind that Andras Halmi, a trusted advisor of The Director, has gone missing. In pursuit of Halmi, Red and Liz narrowly escape a violent confrontation. Meanwhile, Tom ends up in a brutal "Fight Club" to find the one man he thinks will be able to exonerate Liz.
A family tragedy in Samar's past resurfaces when the Task Force hunt for an elusive international terrorist. The FBI and the Cabal gain significant ground in their search for Liz and Red. Meanwhile, Tom encounters complications in his plan to exonerate Liz.
Red and Liz are unexpectedly separated from each other when Red falls into a dangerous situation. Samar makes a risky decision to help Liz while Tom and Cooper continue on their expedition to exonerate Liz.
With her name finally cleared, Liz attempts to reclaim her former life. Red works with the task force to infiltrate an assembly of high-level criminals at large in a rare, risky opportunity to capture the heads of the world's most lethal organized crime syndicates.
When an associate of Red's is killed with a rare medieval device, Red realizes a lethal vigilante group from the Middle Ages has been resurrected; Liz considers her next move after receiving shocking news.
After a missing child that has been presumed dead turns up alive, Red and Liz work with the taskforce to search for a dangerous woman who may be kidnapping children. Meanwhile, Tom faces shocking consequences after his plan to help Liz goes awry.
After the founder of a successful internet start-up is found dead, Red recognizes the crime scene as the work of a notorious killer. Liz and the task force work with Red to track the murderer through a dangerous underground news source. Meanwhile, Tom faces a life threatening situation, while Liz considers options for her baby.
After a State Department official is found dead in Beijing, Red and Liz link the murder to a secret keeper known as "The Caretaker," who maintains an impenetrable safety deposit vault for criminals. Red and Liz work with the task force to find the Caretaker and his collection of lethal and classified secrets. Meanwhile, Tom makes a risky decision, while Liz persists on her quest to find out more about her mother.
After Red learns that a tactical nuclear weapon is being targeted by thieves, it's a race against the clock as the task force struggles to stop them -- and prevent an imminent nuclear disaster. Meanwhile, Tom and Liz make a decision that will change their relationship forever.
After an unexpected loss devastates the FBI task force, they must track down their assailants; a mysterious group whose agents operate using a worldwide satellite network. Meanwhile, Reddington is forced to confront a ghost from his past -- one who knows many of Red's secrets.
The FBI task force's hunt for revenge nears its endgame. As Reddington and the team close in on the mysterious arch-criminal responsible for recent tragic events, they're forced to operate outside their comfort zone – and outside the law – in order to take down their enemy once and for all.